Complement slows heart cells

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Complement slows heart cells

The complement activation product C5a prevents heart cells from contracting , according to Niederbichler and colleagues on page 53. This finding may help explain the cardiac dysfunction commonly seen in patients with septic shock—a disease caused by bacterial infections that is characterized in part by the robust activation of the complement system. A central component of septic shock is decrea...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2005

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem2031iti2